SWOG clinical trial number
CTSU/E2804

The BeST Trial: A Randomized Phase II study of VEGF, RAF kinase and mTOR Combination Targeted Therapy (CTT) with Bevacizumab, Sorafenib and Temsirolimus in Advanced Renal Cell Carcinoma

Closed
Phase
Published
Abbreviated Title
Advanced Renal
Activated
04/01/2008
Closed
12/10/2010
Participants
CTSU

Research committees

Genitourinary Cancer

Treatment

Bevacizumab BAY 43-9006 CCI-779

Eligibility Criteria Expand/Collapse

The Southwest Oncology Group has endorsed this study through the Cancer Trials Support Unit (CTSU) of the National Cancer Institute.

Please contact the CTSU directly by either phone (1-888-823-5923) or on the CTSU web site (http://www.ctsu.org/) for information and registration procedures.

Publication Information Expand/Collapse

2015

BEST: A randomized phase II study of vascular endothelial growth factor, RAF kinase, and mammalian target of rapamycin combination targeted therapy with bevacizumab, sorafenib, and temsirolimus in advanced renal cell carcinoma-a trial of the ECOG-ACRIN Cancer Research Group (E2804)

KT Flaherty;J Manola;M Pins;D McDermott;MB Atkins;JP Dutcher;DJ George;KA Margolin;RS DiPaola Journal of Clinical Oncology Jul 20;33(21):2384-2391

PMid: PMID26077237 | PMC number: PMC4500832

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Research Committee(s)
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Activated
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Accrual
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