Myeloma Specimen Repository Protocol, Ancillary

Pts must be currently registered on a Southwest Oncology Group treatment study (SWOG or Intergroup) for multiple myeloma, smoldering myeloma, Waldenstrom's macroglobulinemia, monoclonal gammopathy of undetermined significance, or amyloidosis. Pts who are already enrolled on active SWOG treatment protocols are eligible for this study. A minimum of 3 ml of bone marrow aspirate and at least one tube of blood (preferably two tubes of blood), will be collected from each pt. Pretreatment specimens must be submitted to be eligible for this study. A pt may be registered on this protocol only once. If a pt on this study subsequently enters another treatment protocol related to this study, then specimens can be submitted according to the procedures of this protocol, and the pt need not be registered again on this study.