Randomized Phase III Trial of Carboplatin and Paclitaxel plus Tirapazamine versus Carboplatin and Paclitaxel in Patients with Advanced Non-Small Cell Lung Cancer - Cisplatin, Paclitaxel, Tirapazamine vs. Cisplatin, Paclitaxel - Specimen submission per S9925
Research committees
Treatment
Eligibility Criteria Expand/Collapse
This study has been approved by NCI's Central Institutional Review Board.
Publication Information Expand/Collapse
2018
Survival by Hispanic Ethnicity among Cancer Patients Participating in SWOG Clinical Trials
PMid: PMID29370458 | PMC number: PMC5963502
2017
History of diabetes and outcome among participants 65 or older in SWOG clinical trials
PMid: PMID30657402 | PMC number: PMC6640843
2016
PMid: PMID27325863 | PMC number: PMC5012713
2014
Comparison of survival outcomes among cancer patients treated in and out of clinical trials
PMid: PMID24627276 | PMC number: PMC3982777
Association between BMI at treatment initiation and cancer survival across multiple SWOG trials
2013
PMid: PMID23910067 | PMC number: PMC4122504
2012
PMid: PMID23253224 | PMC number: Reviews are not within the scope of the Public Access Policy
2009
Japan-USA common arm analysis of paclitaxel-carboplatin in advanced non-small cell lung cancer: a model for assessing population-related pharmacogenomics [PMC2717760; PMID19470925]
Chemotherapy outcomes by histologic subtype of non-small cell lung cancer (NSCLC): analysis of the SWOG database for antimicrotubule-platinum therapy
2008
Disease control rate at 8 weeks predicts clinical benefit in advanced non-small-cell lung cancer: results from Southwest Oncology Group randomized trials [PMID18202421]
Lower osteopontin plasma levels are associated with superior outcomes following platinum-based chemotherapy in advanced non-small cell lung cancer patients: Southwest Oncology Group Trial S0003 [PMC2653139; PMID18779603]
The Southwest Oncology Group: progress in cancer research [PMID18929152]
Cooperative group research efforts in lung cancer 2008: focus on advanced-stage non-small-cell lung cancer
PMid: PMID19073517 | PMC number: (Reviews are not within the scope of the Public Access)
2007
Pharmacogenomic (PG) analysis of Japan-SWOG common arm study in advanced stage non-small cell lung cancer (NSCLC): a model for testing population-related pharmacogenomics
Toxicity and survival by sex in patients with advanced non small cell lung carcinoma (NSCLC) on modern Southwest Oncology Group (SWOG) trials.
2006
Elevated osteopontin (OPN) plasma levels are highly prognostic in advanced non-small cell lung cancer (NSCLC): Analysis of SWOG S0003
Second Japan-SWOG common arm analysis of paclitaxel/carboplatin in advanced stage non-small cell lung cancer (NSCLC): a model for testing population-related pharmacogenomics
2005
Phase III trial of paclitaxel plus carboplatin with or without tirapazamine in advanced non-small-cell lung cancer: Southwest Oncology Group trial S0003
Plasma markers of tumor hypoxia-angiogenesis as predictors of therapeutic response
2004
Japan-SWOG common arm analysis of paclitaxel/carboplatin in advanced stage non-small cell lung cancer (NSCLC): a model for prospective comparison of cooperative group trials
Hypoxia-related markers in the plasma of patients with advanced non-small cell lung cancer (NSCLC) and survival from chemotherapy: Southwest Oncology Group (SWOG) S0003
Mutant DNA in plasma of lung cancer patients; potential for monitoring response to therapy
2003
S0003: Paclitaxel/carboplatin (PC) v PC + tirapazamine (PCT) in advanced non-small cell lung cancer (NSCLC). A phase III Southwest Oncology Group (SWOG) trial.
Hypoxia-induced proteins in plasma of patients on the Southwest Oncology Group (SWOG) S0003 trial in advanced non-small cell lung carcinoma (NSCLC)
S0003: paclitaxel/carboplatin (PC) versus PC + tirapazamine (PCT) in advanced non-small cell lung cancer (NSCLC). a phase III Southwest Oncology Group (SWOG) trial