SWOG clinical trial number
SWOG-9300

A Randomized Phase II Evaluation of All Trans-Retinoic Acid (ATRA) with Interferon-Alfa 2a (IFN-alfa 2a) or All Trans-Retinoic Acid with Hydroxyurea (HU) in Patients with Newly Diagnosed Chronic Myelogenous Leukemia in Chronic Phase

Closed
Phase
Accrual
95%
Abbreviated Title
ATRA/IFN vs ATRA/HU for New CML
Activated
10/01/1993
Closed
12/01/1999
Participants
NCORP, Members, ECOG

Research committees

Leukemia

Treatment

Hydroxyurea All trans retinoic acid Interferon alpha 2a

Eligibility Criteria Expand/Collapse

Pathological diagnosis of CML in chronic phase, Ph1+, no prior therapy for CML other than hydroxyurea and/or leukopheresis of < 3 wks total duration within last 3 months, PS 0-1.