Phase III Study of Three Intensive Post-Remission Therapies in Adult Acute Non-Lymphocytic Leukemia: Comparison of Autologous Bone Marrow Transplantation, Intensive Chemotherapy and Allogeneic Bone Marrow Transplantation

Resistance prediction in AML: analysis of 4,601 patients from MRC/NCRI, HOVON/SAKK, SWOG, and MD Anderson Cancer Center

R Walter;M Othus;AK Burnett;B Lowenberg;H Kantarjian;G Ossenkoppele;R Hills;F Ravandi;A Evans;SA Pierce;F Appelbaum;E Estey Leukemia 29(2):312-320

PMid: PMID25113226 | PMC number: PMC4318722

Unsuccessful cytogenetic analysis is a poor prognostic feature in acute myeloid leukemia

B Medeiros;M Othus;E Estey;M Fang;F Appelbaum British Journal of Haematology 28(2):245-250;

PMid: PMID24383844 | PMC number: PMC4117470

Significance of FAB subclassification of "acute myeloid leukemia, not otherwise specified" in the 2008 WHO classification: analysis of 5,848 newly diagnosed patients

RB Walter;M Othus;A Burnett;B Lowenberg;H Kantarjian;GJ Ossenkoppele;RK Hills;K van Montfort;F Ravandi;A Evans;SA Pierce;F Appelbaum;EH Estey Blood 121(13):2424-2431;

PMid: PMID23325837 | PMC number: PMC3612855

Prediction of therapeutic resistance in adult acute myeloid leukemia: analysis of 4,550 newly diagnosed patients from MRC/NCRI, HOVON, SWOG, and MD Anderson Cancer Center

R Walter;M Othus;AK Burnett;AK Burnett;B Lowenberg;H Kantarjian;GJ Ossenkoppele;RK Hills;F Ravandi;A Evans;SA Pierce;F Appelbaum;E Estey Blood 122:64; American Society of Hematology annual meeting (Dec 7-10, 2013), oral;

Impact of residual normal metaphases in core binding factor acute myeloid leukemia

B Medeiros;M Othus;M Fang;F Appelbaum;E Estey Cancer 118(9):2420-2423;

PMid: PMID21928314 | PMC number: PMC3490403

Prognostic significance of the French-American-British (FAB) morphologic subclassification of "acute myeloid leukemia, not otherwise specified" in the 2008 WHO classification: analysis of 5,848 newly diagnosed patients from HOVON, MRC, SWOG, and MD Anderson Cancer Center

R Walter;M Othus;AK Burnett;B Lowenberg;H Kantarjian;G Ossenkoppele;RK Hills;K van Montfort;F Ravandi;S Pierce;F Appelbaum;E Estey Blood 120(21)abst. 540; American Society of Hematology Annual Meeting, oral;

Influence of residual normal metaphases in acute myeloid leukemia patients with monosomal karyotype [PMID21330329; PMC3069244]

B Xie;M Othus;B Medeiros;M Fang;F Appelbaum;E Estey Haematologica 96(4):631-632

Cytarabine dose for acute myeloid leukemia. (Letter to the Editor) [PMID21631340]

B Medeiros;M Othus;F Appelbaum New England Journal of Medicine 364(11):2167-2168

Prediction of early death following induction therapy for newly diagnosed acute leukemia with pretreatment risk scores: a novel paradigm for treatment assignment

R Walter;M Othus;G Borthakur;F Ravandi;J Cortes;S Pierce;F Appelbaum;H Kantarjian;E Estey Journal of Clinical Oncology, 29(33):4417-23;

PMid: PMID21969499 | PMC number: PMC3221524

Prognostic impact of monosomal karyotype in young adults and elderly acute myeloid leukemia: the Southwest Oncology Group experience [PMID: 20562328; NIHMSID244631]

BC Medeiros;M Othus;M Fang;D Roulston;FR Appelbaum Blood 116(13):2224-2228

PMid: PMID20562328 | PMC number: PMC3709629

Influence of residual normal metaphases in patients with monosomal karyotype

B Xie;M Othus;B Medeiros;M Fang;F Appelbaum;E Estey Blood 116:Abstract 1671; ASH 2010 meeting; poster presentation

Age and acute myeloid leukemia

FR Appelbaum;H Gundacker;DR Head;ML Slovak;CL Willman;JE Godwin;JE Anderson;SH Petersdorf Blood 107(9):3481-3485

Gene expression profiling of adult acute myeloid leukemia identifies novel biologic clusters for risk classification and outcome prediction.

CS Wilson;GS Davidson;SB Martin;E Andries;J Potter;R Harvey;K Ar;Y Xu;KJ Kopecky;DP Ankerst;H Gundacker;ML Slovak;M Mosquera-Caro;IM Chen;DL Stirewalt;M Murphy;FA Schultz;H Kang;X Wang;JP Radich;FR Appelbaum;SR Atlas;J Godwin;CL Willman Blood 108(2):685-696

The clinical spectrum of adult acute myeloid leukaemia associated with core binding factor translocations.

FR Appelbaum;KJ Kopecky;MS Tallman;ML Slovak;HM Gundacker;HT Kim;GW Dewald;HM Kantarjian;SR Pierce;EH Estey British Journal of Haematology 135:165-173

Letter to the editor: A retrospective study of 69 patients with t(6;9)(p23;q34) AML emphasizes the need for a prospective, multicenter initiative for rare 'poor prognosis' myeloid malignancies

ML Slovak;H Gundacker;CD Bloomfield;G Dewald;FR Appelbaum;RA Larson;MS Tallman;JM Bennett;DL Stirewalt;S Meshinchi;CL Willman;Y Ravindranath;TA Alonzo;AJ Carroll;SC Raimondi;NA Heerema Leukemia 20:1295-1297

The significance of trisomy 8 in myeloid leukemia: a Southwest Oncology Group (SWOG) study.

ML Slovak;H Gundacker;SR Wolman;FR Appelbaum American Journal of Human Genetics 69(4):232(#285)

Glutathione S-transferase theta 1 gene deletion and risk of acute myeloid leukemia

C Crump;C Chen;FR Appel baum;KJ Kopecky;SM Schwartz;CL Willman;ML Slovak;NS Weiss Cancer Epidemiology Biomarkers & Prevention 9:457-460

Karyotypic analysis predicts outcome of preremission and postremission therapy in adult acute myeloid leukemia: a Southwest Oncology Group/Eastern Cooperative Oncology Group study.

ML Slovak;KJ Kopecky;PA Cassileth;DP Harrington;KS Theil;A Mohamed;E Paietta;CL Willman;DR Head;JM Rowe;SJ Forman;FR Appelbaum Blood 96(13):4075-4083

Cloning and chromosomal localization of the gene encoding human cyclin D-binding Myb-like protein (hDMP1).

SM Bodner;CW Naeve;KM Rakestraw;BG Jones;VA Valentine;MB Valentine;FW Luthardt;CL Willman;SC Raimondi;JR Downing;MF Roussel;CJ Sherr;AT Look Gene 229:223-228

Karyotypic analysis predicts outcome of pre-and post- remission therapy in adult acute myeloid leukemia (AML): A SWOG/ECOG intergroup study.

ML Slovak;KJ Kopecky;PA Cassileth;DH Harrington;K Theil;A Mohamed;A Chung;E Paietta;C Willman;DR Head;SJ Forman;FR Appelbaum Blood 92(10)(Suppl.1):678a(#2795)

Chemotherapy compared with autologous or allogeneic bone marrow transplantation in the management of acute myeloid leukemia in first remission

PA Cassileth;DP Harrington;FR Appelbaum;HM Lazarus;JM Rowe;E Paietta;C Willman;DD Hurd;JM Bennett;KG Blume;DR Head;PH Wiernik New England Journal of Medicine 339(23):1649-1656

Cell cycle arrest and therapeutic sensitivity in de novo AML.

D Banker;C Willman;M Groudine;F Appelbaum Blood 90(10)Suppl.1:67a(#290)

Comparison of autologous bone marrow transplant (AUTOBMT) with high-dose cytarabine (HDAC) in adult acute myeloid leukemia (AML) in first remission (CR1): an ECOG intergroup study.

P Cassileth;D Harrington;E Paietta;H Lazarus;F Appelbaum;K Blume;J Bennett;D Hurd;C Willman;M Slovak;P Wiernik Proc of the American Society of Clinical Oncology 16:89a(#311)

Measurement of spontaneous and therapeutic agent-induced apoptosis with BCL-2 protein expression in acute myeloid leukemia.

DE Banker;M Groudine;T Norwood;FR Appelbaum Blood 89(1):243-255

Identification of the chimeric protein product of the CBFB-MYH11 fusion gene in inv(16) leukemia cells.

PP Liu;C Wijmenga;A Hajra;TB Blake;CA Kelley;RS Adelstein;A Bagg;J Rector;J Cotelingam;CL Willman;FS Collins Genes Chromosomes and Cancer 16:77-87

Spontaneous and therapeutic agent-induced apoptosis with BCL-2 protein expression in acute myeloid leukemia.

DE Banker;M Groudine;FR Appelbaum Blood 88(10)Suppl:665a(#2649)

Characterization and rapid diagnostic utility of a novel antibody detecting the CBFB/SMMHC fusion protein of inversion(16)/t(16;16) associated acute myeloid leukemia.

DS Viswanatha;IM Chen;PP Liu;ML Slovak;C Rankin;CL Willman Blood 88(10)Suppl:664a(#2646)

The biological significance of the multidrug resistance gene MRP in inversion 16 leukemias.

BJ Kuss;RG Deeley;SPC Cole;CL Willman;KJ Kopecky;SR Wolman;HJ Eyre;DF Callen Leukemia and Lymphoma 20:357-364

Trisomy 11: an association with stem/progenitor cell immunophenotype.

ML Slovak;ST Traweek;CL Willman;DR Head;KJ Kopecky;RE Magenis;FR Appelbaum;SJ Forman British Journal of Hematology 90:266-273

An AML1/ETO fusion transcript is consistently detected by RNA-based polymerase chain reaction in acute myelogenous leukemia containing the t(8;21) (q22;q22).

JR Downing;DR Head;AM Curcio-Brint;MG Hulshof;TA Motroni;SC Raimondi;AJ Carroll;HA Drabkin;CL Willman;KS Theil;CI Civin;P Erikson Blood 81(11):2860-2865

HRX involvement in de novo and secondary leukemias with diverse chromosome 11q23 abnormalities.

SP Hunger;DC Tkachuk;MD Amylon;MP Link;AJ Carroll;Jl Welborn;CL Willman;ML Cleary Blood 81(12):3197-3203