SWOG clinical trial number
SWOG-8590 (INT-0034)

Phase III Study to Determine the Effect of Combining Chemotherapy with Surgery and Radiotherapy for Resectable Squamous Cell Carcinoma of the Head and Neck

Closed
Phase
Published
Abbreviated Title
Phase III Study to Determine the Effect of Combining Chemotherapy with Surgery and Radiotherapy for Resectable Squamous Cell Carcinoma of the Head and Neck
Activated
02/20/1985
Closed
02/01/1990

Research committees

Head and Neck Cancer

Publication Information Expand/Collapse

2000

The influence of beam energy on the outcome of postoperative radiotherapy in head and neck cancer patients: secondary analysis of RTOG 85-03

A Aref;BA Berkey;JG Schwade;J Ensley;DE Schuller;RE Haselow;TJ Ervin;GE Laramore Int J Radiat Oncol Biol Phys 47(2):389-394

1999

The influence of beam energy on the outcome of postoperative radiotherapy in head and neck cancer patients: secondary analysis of RTOG 85-03

A Aref;BA Berkey;JG Schwade;J Ensley;DE Schuller;RE Haselow;TJ Ervin;GE Laramore Int J Radiat Oncol Biol Phys 45(3)Suppl:274(#1034)

1997

DNA content parameters in advanced, resectable squamous cell carcinomas of the head and neck (SCCHN); analysis of INT 0034, a RTOG (8503)-administered head and neck cancer intergroup trial.

JF Ensley;G Laramore;T Pajak;M Alonso;H Pietraskiewicz;K Fu;A Forastiere;G Adams;D Schuller;M Al-Sarraf Proc of the American Society of Clinical Oncology 16:390a(#1393)

Radiotherapy (RT) versus chemotherapy (CT) followed by RT in resected and negative margins head and neck cancers (HNC). Intergroup study 0034.

M Al-Sarraf;T Pajak;G Laramore;JR Jacobs;JF Ensley;S Ahmad;D Schuller;R Haselow;E Vokes;A Markoe;R Byhardt Proc of the American Society of Clinical Oncology 16:392a(#1399)

1994

Chemotherapy as predictor of compliance.

JR Jacobs;RR Casiano;DE Schuller;TF Pajak;GE Laramore;M Al-Sarraf Journal of Surgical Oncology 55:143-148

The effect of perioperative blood transfusion on survival in head and neck cancer.

DE Schuller;C Scott;KM Wilson;R Freer;M Al-Sarraf;J Jacobs;K Ahmad;R Casiano;G Laramore Archives of Otolaryngology-Head and Neck Surgery 120:711-716

Surgical reporting instrument designed to improve outcome data in head and neck cancer trials.

EA Weymuller;K Ahmad;RR Casiano;G Laramore;DE Schuller;M Al-Sarraf;CB Scott;JR Jacobs Annals of Otology Rhinology and Laryngology 103:499-509

1993

Implications of positive surgical margins.

JR Jacobs;K Ahmad;R Casiano;DE Schuller;C Scott;GE Laramore;M Al-Sarraf Laryngoscopy 103:64-68

Is a surgical resection leaving positive margins of benefit to the patient with locally advanced squamous cell carcinoma of the head and neck: A comparative study using the Intergroup study 0034 and the Radiation Therapy Oncology Group head and neck database.

GE Laramore;CB Scott;DE Schuller;RE Haselow;TJ Ervin;R Wheeler;M Al-Sarraf;RA Gahbauer;JR Jacobs;JG Schwade;BH Campbell International J of Radiation Oncology Biology Physics 27:1011-1016

Postoperative irradiation in head and neck cancer.

JS Cooper International Journal Oncology Biology Physics 26(1):181-182

1992

Adjuvant chemotherapy for resectable squamous cell carcinomas of the head and neck: Report on Intergroup study 0034.

GE Laramore;CB Scott;M Al-Sarraf;RE Haselow;TJ Ervin;R Wheeler;JR Jacobs International J of Radiation Oncology Biology Physics 23:705-713

The effect of peri-operative blood transfusion on survival in head and neck cancer.

DE Schuller;C Scott;K Wilson;R Freer;M Al-Sarraf;J Jacobs;R Ahmad;R Casiano;G Laramore Third International Conference on Head and Neck Cancer 103:(#211)

Chemotherapy as predictor of compliance.

JR Jacobs;R Casiano;DE Schuller;TF Pajak;GE Laramore;M Al-Sarraf Third International Conference on Head and Neck Cancer 62:(#49)

An association between DNA diploid tumors and margin negative surgical resections: Implications for adjuvant trials in patients with advanced, resectable squamous cell carcinomas of the head and neck (SCCHN).

JF Ensley;H Pietraszkiewicz;M Del Alonso;Z Maciorowski;F deBraud ASCO 11:242(#779)

Phase III study comparing sequential chemotherapy (CT) and radiotherapy (RT) to RT for resected and negative margins squamous cell carcinoma of the head and neck: Intergroup study #0034.

M Al-Sarraf;CB Scott;K Ahmad;JG Schwade;D Schuller;GE Laramore;J Jacobs Proc of the American Society of Clinical Oncology 11:242(#778)

Unappreciated impact of potentially "curative" surgery (pcs) in multi-modality head and neck (h+n) trials upon sample size requirements.

TF Pajak;JR Jacobs International Conference on Head and Neck cancer-San Francisco :121(#283)

Chemotherapy as predector of compliance.

JR Jacobs;RA Casiano;DE Schulller;TF Pajak;GE Laramore;M Al-Sarraf International Conference on Head and Neck Cancer 62(#49)

Is a surgical resection leaving positive margins of benefit to the patient with locally-advanced squamous cell carcinoma of hte head and neck?

GE Laramore;CB Scott;DE Schuller;RE Haselow;TJ Ervin;R Wheeler;M Al-Sarraf;RA Gahbauer;JR Jacobs;JG Schwade;BH Campbell Proc of the 34th Annual ASTRO Meeting 24:173(#83)

Adjuvant chemotherapy for resectable squamous cell carcinoma of the head and neck. Report on intergroup study 0034.

WK Hong International Journal of Radiation Oncology Biology Physics 23(4):885-886

1991

Development of surgical quality-control mechanisms in large scale prospective trials: Head & Neck Intergroup Report.

JR Jacobs;RF Pajak;E Weymuller;D Sessions;DE Schuller Head and Neck 13(1):28-32

Do otolarynologist-head and neck surgeons and/or chemotherapy have a role in the treatment of head and neck cancer?

DE Schuller Otolaryngology-Head and Neck Surgery 117:498-501

Adjuvant chemotherapy for resectable squamous cell carcinomas of the head and neck: Report on intergroup study 0034.

GE Laramore;CB Scott;M Al-Sarraf;RE Haselow;TJ Ervin;R Wheeler;JR Jacobs Intl Journal of Radiation Oncology Biology Physics 21(Suppl.1):190(#140)

Development of surgical quality-control mechanisms in large-scale prospective trials: Head and neck intergroup report.

JR Jacobs;TF Pajak;EA Weymuller;D Sessions;DE Schuller Head and Neck 13:28-32

1989

Combine therapy for resectable head and neck cancer: A phase III study.

DE Schuller;G Laramore;M Al-Sarraf;J Jacobs;TF Pajak Archives of Otolaryngology-Head and Neck Surgery 115:364-368

1988

Development of surgical quality control mechanism in large scale prospective trials - A head and neck intergroup report.

JR Jacobs;T Pajak;E Weymuller;D Sessions;D Schuller American Society of Head and Neck Surgeons-Intl Conference :84(#145)

Phase III study to determine the effect of combining chemotherapy with surgery and radiotherapy for resectable sqamous cell carcinom of the head and neck.

DE Schuller;GE Laramore;M Al-Sarraf;JJ Jacobs American Society of Head and Neck Surgerons-Intl Conference :55(#32)

Adequacy of sample sizes: Head and Neck intergroup experience (RTOG, SWOG, ECOG, CALGB, NCOG, and SECSG).

TF Pajak;C Scott;G Laramore;JR Jacobs;M Al-Sarraf;DE Schuller American Society of Head and Neck Surgerons-Intl Conference :84(#146)