SWOG clinical trial number
SWOG-8326/27

Evaluation of Combination Chemotherapy Using High Dose Ara-C in Adult Acute Leukemia and Chronic Granulocytic Leukemia in Blastic Crisis

Closed
Phase
Accrual
99%
Published
Abbreviated Title
Evaluation of Combination Chemotherapy Using High Dose Ara-C in Adult Acute Leukemia and Chronic Granulocytic Leukemia in Blastic Crisis
Activated
04/26/1985
Closed
12/15/1992

Research committees

Leukemia

Publication Information Expand/Collapse

2010

The effect of complete remission (CR) and CR with incomplete platelet recovery (CRp) on outcome in acute myeloid leukemia: a combined eastern cooperative oncology group (ECOG), Southwest Oncology Group (SWOG), and M.D. Anderson Cancer Center study

Journal of Clinical Oncology 28(10):1766-1771;

2000

Microsatellite Instability is not a defining genetic feature of acute myeloid leukemogenesis in adults: results of a retrospective study of 132 patients and review of the literature

LM Rimsza;KJ Kopecky;J Ruschulte;I-M Chen;ML Slovak;C Karanes;J Godwin;A List;CL Willman Leukemia 14:1044-1051

1999

A phase II comparison of high dose ARA-C (HIDAC) vs HIDAC plus mitoxantrone in the treatment of first relapsed or refractory acute myeloid leukemia. A Southwest Oncology Group study.

C Karanes;KJ Kopecky;MR Grever;HE Hynes;EH Kraut;RH Vial;A Lichtin;S Nand;WE Samlowski;FR Appelbaum Leukemia Research 23(9):787-794

1995

Trisomy 11: an association with stem/progenitor cell immunophenotype.

ML Slovak;ST Traweek;CL Willman;DR Head;KJ Kopecky;RE Magenis;FR Appelbaum;SJ Forman British Journal of Hematology 90:266-273

1992

Evaluation of combination chemotherapy using high dose ARA-C with and without mitoxantrone in the treatment of first relapse acute myeloid leukemia. A Southwest Oncology Group study.

C Karanes;K Kopecky;M Grever;F Appelbaum Blood 80:114A

The relationship of the stem cell phenotype and lineage commitment to the multidrug resistance phenotype in acute leukemia.

C Spier;A List;C Karanes;T Grogan;C Willman;FR Appelbaum U.S. Canadian Academy of Pathology Lab Investment 5(1):88A

1991

Multidrug resistance in CD34+ acute leukemia correlates with non-lymphoid lineage.

C Spier;A List;CL Willman;F Appelbaum;C Karanes;D Head Blood 78:175a

Multiparameter analysis of acute mixed lineage leukemia: Correlation of aB/Myeloid immunophenotype and immunoglobulin and T-cell gene rearrangements with the presence of the Philadelphia chromosome translocation in acute leukemias with

IA Saikevych;DP Kerrigan;TS McConnell;DR Head;FR Appelbaum;CL Willman Leukemia 5(5):373-382

1990

Multiparameter analysis of acute mixed lineage leukemia: Correlation of B/Myeloid immunophenotype and immunoglobulin and T-cell gene rearrangements with the presence of the Philadelphia chromosome translocation in acute leukemias with myeloid morphology.

IA Saikevych;DP Kerrigan;TS McConnell;D Head;FR Appelbaum;CL Willman Leukemia 5(5):373-382

1989

Increased risk of early death (ED) with high dose ara-C (HDAC)and m-AMSA compared to HDAC alone or HDAC and mitoxantrone (MITOX) inhigh risk nonlymphocytic leukemia (ANL)

C Karanes;KJ Kopecky;BGM Durie;MR Grever ASCO 8:201(#783)