SWOG clinical trial number
S1826
A Phase III, Randomized Study of Nivolumab (Opdivo) Plus AVD or Brentuximab Vedotin (Adcetris) Plus AVD in Patients (Age >/= 12 years) with Newly Diagnosed Advanced Stage Classical Hodgkin Lymphoma
Closed
Phase
Accrual
100%
Abbreviated Title
Phase III Study of AVD plus nivolumab or BV in pts >/= 12 years in newly diagnosed, advanced cHL
Status Notes
Permanently closed to accrual, effective December 01, 2022, 12:00 p.m. Pacific Time
Activated
07/19/2019
Closed
12/01/2022
Participants
ALL NATIONAL CLINICAL TRIALS NETWORK MEMBERS LISTED ON TITLE PAGE
Research committees
Lymphoma
Treatment
Doxorubicin
Filgrastim
Vinblastine Sulfate
Radiation Therapy
Pegfilgrastim
Nivolumab
Brentuximab Vedotin
Dacarbazine
RT
Eligibility Criteria Expand/Collapse
See Section 5.0 of the S1826 protocol posted on www.ctsu.org
Publication Information Expand/Collapse
2024
Late Cardiac Toxic Effects Associated With Treatment Protocols for Hodgkin Lymphoma in Children
PMid: PMID38241048 | PMC number: PMC10799264
Nivolumab-AVD or Standard of Care in Advanced Stage Classic Hodgkin Lymphoma
PMid: PMID39413375 | PMC number: PMC11488644
2023
2021
An Intergroup Approach for Advanced Stage Classical Hodgkin Lymphoma (cHL) in Adolescents and Young Adults (AYA): SWOG S1826
Addressing the Paucity of AYA Clinical Trials Through Pediatric and Adult Partnership
2020
PMid: PMID32917781
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SWOG Clinical Trial Number
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Research Committee(s)
Lymphoma
Immunomolecular Therapeutics
Activated
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Open
Phase