Trial & Business Updates:

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Amendments, Revisions, Memoranda

S0127Phase II

Amendment #1

A Phase II Study of OSI-774 (NSC #718781) in Unresectable or Metastatic Adenocarcinoma of the Stomach and Gastroesophageal Junction
Study Coordinator(s)Tomislav Dragovich, M.D., Ph.D, James L. Abbruzzese, M.D.
ParticipantsMembers, NCORP
S0211Phase II

Memorandum

A Phase II Trial of STI571 for the Treatment of Platinum and Taxane Refractory Stage III and IV Epithelial Ovarian Cancer and Primary Peritoneal Cancer
Study Coordinator(s)Andy Jang, M.D., Sharon Wilczynski, M.D.,Ph.D.
ParticipantsMembers, NCORP, Medical Oncologists, Surgeons, Pathologists
S9915Phase II

Revision #7

A Phase II Study of PN401, 5-FU, and Leucovorin in Unresectable or Metastatic Adenocarcinoma of the Stomach.
Study Coordinator(s)James H. Doroshow, M.D., John S. Macdonald, M.D.
ParticipantsMembers, NCORP
SWOG-8624Phase III

Memorandum

A Phase III Randomized Trial of Combination Therapy for Multiple Myeloma; Comparison of (1) VMCP/VBAP to VAD or VMCPP/VBAPP for Induction; (2) Alpha-2b Interferon or No Therapy for Maintenance; and 3) Alpha-2b Interferon + Dexamethasone for Incomplete or Non-Responders; and (4) VAD Plus Verapamil For Incomplete or Non-Responders on VAD
Study Coordinator(s)Bart Barlogie, M.D.,Ph.D., Sheikh Saeed, M.D.
SWOG-8993Phase II

Memorandum

Phase II Study of High Dose Melphalan with Hemopoietic Stem Cell Support and GM-CSF in Refractory Multiple Myeloma (MM)
Study Coordinator(s)Bart Barlogie, M.D.,Ph.D.
SWOG-9028Phase III

Memorandum

A Phase III Randomized Trial of Combination Therapy for Multiple Myeloma Comparison of (1) VAD to VAD/ Quinine for Induction with Crossover to VAD/ Quinine for VAD Induction Failures; (2) Alpha-2b Interferon or Alpha-2b Interferon plus Prednisone for Remission Maintenance
Study Coordinator(s)Bart Barlogie, M.D.,Ph.D., Thomas M. Grogan, M.D.
SWOG-9400Phase II

Memorandum

Treatment of Adult Lymphoblastic Leukemia: A Phase II Trial of An Induction Regimen Including PEG-L-Asparaginase in Previously Untreated Patients, Followed By Allogeneic Bone Marrow Transplantation or Further Chemotherapy In First Complete Remission
Study Coordinator(s)Stephen J. Forman, M.D., Chatchada Karanes, M.D., Nelson J.A. Chao, M.D.

Other New Items

  • IP - Pts Must Be Informed
  • AC - Consent Must Be Amended
  • CBR - No Registration Allowed until IRB Review
  • RC - Formal Re-consent Required
  • FBR - Full Board Review Required
  • ER - Expedited Review Acceptable
  • NR - No IRB Review Required