SWOG clinical trial number
SWOG-9402
Phase III Intergroup Randomized Comparison of Radiation Alone Vs. Pre-Radiation Chemotherapy for Pure and Mixed Anaplastic Oligodendrogliomas
Closed
Phase
Published
Research committees
Brain Cancer
Treatment
Radiation Therapy
PCV
Eligibility Criteria Expand/Collapse
Pathologic evidence of unifocal or multifocal supratentorial pure or mixed anaplastic oligodendroglioma; patients with low grade glioma are eligible provided they now have a biopsy proven pure or mixed anaplastic oligodendroglioma and have not been treated previously with either RT or chemo; KPS >= 60, AGC >=1,500/µl, platelet count >=150,000/µl, creatinine < / = 1.5 x normal, bilirubin, SGOT, alkaline phos.< / = 2 x normal; no prior RT or chemotherapy.
Publication Information Expand/Collapse
2010
Cognition and quality of life after chemotherapy plus radiotherapy (RT) vs. RT for pure and mixed anaplastic olilgodendrogliomas: radiation therapy oncology group trial 9402 (RTOG; NCCTG; SWOG; NCIC CTG; ECOG) [PMID19783377; PMC2878934]
2006
Phase III trial of chemotherapy plus radiotherapy compared with radiotherapy alone for pure and mixed anaplastic oligodendroglioma: Intergroup Radiation Therapy Oncology Group Trial 9402
2004
An intergroup randomized controlled clinical trial (RCT) of chemotherapy plus radiation (RT) versus RT alone for pure and mixed anaplastic oligodendrogliomas: initial report of RTOG 94-02