Phase II Study of High Dose ARA-C/Mitoxantrone for the Treatment of Relapsed/Refractory Acute Lymphocytic Leukemia

Response to high dose cytarabine (HIDAC) as first salvage for relapsed acute lymphocytic leukemia is not affected by prior exposure to HIDAC

A Advani;H Gundacker;N Nyatanga;PJ Rosen;M Sekeres;M Kalaycio;R Sobecks;E Copelan;F Appelbaum Blood 118(21):abstract 2594; American Society of Hematology, poster;

A phase II study of high dose Ara-C and mitoxantrone for treatment of relapsed or refractory adult acute lymphoblastic leukemia. A Southwest Oncology Group study.

PJ Rosen;C Rankin;DR Head;DH Boldt;FW Luthardt;T Norwood;RP Pugh;C Karanes;FR Appelbaum Leukemia Research 24:183-187

Cloning and chromosomal localization of the gene encoding human cyclin D-binding Myb-like protein (hDMP1).

SM Bodner;CW Naeve;KM Rakestraw;BG Jones;VA Valentine;MB Valentine;FW Luthardt;CL Willman;SC Raimondi;JR Downing;MF Roussel;CJ Sherr;AT Look Gene 229:223-228

Detection of cancer cells with PCR-telomerase assay in human tumor biopsies.

E Raymond;S Sharma;D Sun;RE Champlin;H Soda;DH Boldt;DD Von Hoff Proc of the American Society of Clinical Oncology 16:93a

Inactivation of cell cycle regulatory genes occurs frequently in adult acute lymphoblastic leukemia (ALL): potential role for p16, p13, Rb, and p53 in leukemogenesis.

W Stock;C Rankin;D Sher;P Eagan;T Tsai;D Boldt Proc of the American Society of Clinical Oncology 16:552a(#1993)

Comparison of tumor suppressor gene inactivation in de novo and relapsed adult acute lymphoblastic leukemia (ALL).

T Tsai;S Davalath;C Rankin;F Appelbaum;DH Boldt American Society of Clinical Oncology 15:358(#1052)

Tumor suppressor gene alteration in adult acute lymphoblastic leukemia (ALL). Analysis of retinoblastoma (Rb) and p53 gene expression in lymphoblasts of patients with de novo, relapsed, or refractory ALL treated in Southwest Oncology Group studies.

T Tsai;S Davalath;C Rankin;JP Radich;D Head;FR Appelbaum;DH Boldt Leukemia 10:1901-1910