SWOG clinical trial number
SWOG-9008 (INT-0116) (RTOG-9018) (NCCTG-90-41-51) (ECOG-6290) (CALGB-9195)
Trial of Adjuvant Chemoradiation After Gastric Resection For Adenocarcinoma, Phase III
100% Accrual
Accrual
100%
Closed
100% Accrual
Accrual
100%
Published
Abbreviated Title
Trial of Adjuvant Chemoradiation After Gastric Resection For Adenocarcinoma, Phase III
2012
Assessment of HER2 Gene Amplification in Adenocarcinomas of the Stomach or Gastroesophageal Junction in the INT-0116/SWOG9008 Clinical Trial
MA Gordon;H Gundacker;J Benedetti;J Macdonald;J Baranda;W Levin;N Wick;C Blanke;W Elatre;P Weng;J-Y Zhou;H Lenz;M Press J Clin Oncol 30 (suppl; abstr 4010); American Society of Clinical Oncology 2012 Annual Meeting (June 1-5, 2012, Chicago, IL), poster discussion;
2011
Gastric Cancer: Nagoya is not New York [PMID22010021]
J Macdonald Journal of Clinical Oncology 29(33):4348-4350
2009
Chemoradiation of resected gastric cancer: a 10 year followup of INT0116 (SWOG 9008)
J Macdonald;J Benedetti;SR Smalley;D Haller;S Hundahl;J Jessup;J Ajani;LL Gunderson;B Goldman;JA Martenson Journal of Clinical Oncology 27:15s, abst. #4515
Report from the Radiation Therapy Committee of the Southwest Oncology Group (SWOG): research objectives workshop 2008 [PMID19723641; PMC2978526]
P Okunieff;LA Kachnic;LS Constine;CD Fuller;LE Gaspar;DF Hayes;J Hooks;C Ling;FL Meyskens;PA Philip;D Raben;SR Smalley;GP Swanson;BA Teicher;CR Thomas;B Vikram;MJ Zelefsky;LH Baker Clinical Cancer Research 15(18):5663-5770
2008
The Southwest Oncology Group: progress in cancer research [PMID18929152]
CA Coltman Seminars in Oncology 35(5):545-552
2007
Improved regional control and survival with "low maruyama index" surgery in gastric cancer: autopsy findings from the Dutch D1-D2 trial [PMID17336241]
SA Hundahl;KCJM Peeters;EK Kranenbarg;H Hartgrink;CJH van de Velde Gastric Cancer 10(2):84-86
Gastric cancer: D2 dissection or low maruyama index-based surgery - a debate [PMID17336241]
HO Douglass;SA Hundahl;JS Macdonald;VP Khatri Surgical Oncology Clinics of North America 16(1):133-155
2006
Low maruyama index surgery for gastric cancer [PMID17577616]
SA Hundahl Scandinavian Journal of Surgery 95(4):243-248
2005
Evidence-based recommendations for local-regional control of gastric cancer
SA Hundahl Cancer Investigation 23(4):352-362
Chapter 45 - Stomach
SA Hundahl;JS Macdonald;SR Smalley In: Chang AE, Ganz PA, Hayes DF, et al. (eds). Oncology: An Evidence Based Approach, New York: Springer-Verlag, pgs 680-703
Changing gastric cancer treatment in the United States and the pursuit of quality
SA Hundahl;HJ Wanebo European Journal of Surgical Oncology 31(6):605-615
Low maruyama index surgery for gastric cancer: blinded re-analysis of the Dutch D1-D2 trial
KCMJ Peeters;SA Hundahl;EK Kranenbarg;H Hartgrink;CJH van de Velde World Journal of Surgery 29:1576-1584
2004
Postoperative combined radiation and chemotherapy improves disease-free survival (DFS) and overall sirvival (OS) in resected adenocarcinoma of the stomach and gastroesophageal junction: update o fthe results of Intergroup study INT-0116 (SWOG 9008)
JS Macdonald;S Smalley;J Benedetti;N Estes;DG Haller;JA Ajani;LL Gunderson;M Jessup;JA Martenson American Society of Clinical Oncology GastrointestinaI Cancers Symposium #6
Impact of T and N stage and treatment on survival and relapse in adjuvant rectal cancer: a pooled analysis PMID:15067027
LL Gunderson;DJ Sargent;TE Tepper;N Wolmark;MJ O'Connell;M Begovic;C Allmer;L Colangelo;SR Smalley;DG Haller;JA Martenson;RJ Mayer;TA Rich;JA Ajani;JS MacDonald;CG Willett;RM Goldberg Journal of Clinical Oncology 22(10):1773-1775
Intergroup 0144: A phase III rectal surgical adjuvant study of pelvic radiation (XRT) plus 5-FU based chemotherapy (bolus 5-FU before and after PVI + XRT vs PVI before, during, and after XRT vs biochemically modulated bolus 5-FU and XRT): mature outcome results and pelvic failure analysis
S Smalley;J Benedetti;S Williamson;J Robertson;B Fisher;J Martenson;A Benson;R Mayer;C Cripps;N Estes;J Macdonald Proceedings of American Society for Therapeutic Radiology and Oncology, p. S137, abst. #14
2003
Frequent alterations of B-catenin gene in gastric cancers with microsatellite instability
J Wang;T Shepherd;A Lowy;A Noffsinger;G Stemmermann;C Fenoglio-Preiser Proc of the American Association for Cancer Research 44(2nd.ed): #1199
Report from the Radiation Oncology Committee of the Southwest Oncology Group (SWOG): Research Objectives Workshop 2003 PMID14528084
P Okunieff;RE Meyn;BA Teicher;CR Thomas, Jr.;LE Gaspar;D Raben;S Giri;RS Lavey;AT Turrisi;GP Swanson;SR Smalley American Journal of Clinical Oncology 26(5):522-529
PMid: PMID14528084
2002
B-Catenin mutation is a frequent cause of Wnt pathway activation in gastric cancer
WM Clements;J Wang;A Sarnaik;OJ Kim;JS Macdonald;C Fenoglio-Preiser;J Groden;AM Lowy Cancer Research 62:3503-3506
B-Catenin nuclear staining and mutation in gastric cancer
OJ Kim;J Wang;WM Clements;AA Sarnaik;G Stemmermann;A Noffsinger;G DeVoe;AM Lowy;C Fenoglio-Preiser Modern Pathology 15(1):132a(#551)
Beta-catenin is commonly mutated in human gastric cancers with cyclin D overexpression.
J Wang;ONJ Kim;WM Clements;AA Sarnaik;B Liu;A Noffsinger;G Stemmermann;AM Lowy;CM Fenoglio-Preisor Proc of the American Association for Cancer Research 93:90(#526)
Mutation of the B-catenin gene is a frequent cause of Wnt pathway activation in gastric cancer.
WM Clements;J Wang;A Sarnaik;OJ Kim;JL Groden;C Fenoglio-Preiser;AM Lowy Proc of the American Association for Cancer Research 93:111(#770)
Surgical treatment variation in a prospective, randomized trial of chemoradiotherapy in gastric cancer: the effect of undertreatment.
SA Hundahl;JS Macdonald;J Benedetti;T Fitzsimmons Annals of Surgical Oncology 9(3):278-286
Surgical quality in trials of adjuvant cancer therapy
SA Hundahl Journal of Surgical Oncology 80:177-180
2001
Chemoradiotherapy after surgery compared with surgery alone for adenocarcinoma of the stomach or gastroesophageal junction.
JS Macdonald;SR Smalley;J Benedetti;SA Hundahl;NC Estes;GN Stemmermann;DG Haller;JA Ajani;LL Gunderson;JM Jessup;JA Martenson New England Journal of Medicine 345(10):725-730
E-Cadherin, a and b-catenins in gastric cancer expression
OJ Kim;G Stemmermann;G DeVoe;A Noffsinger;J Macdonald;C Fenoglio-Preiser Modern Pathology 14:88A(#506)
Gastric Cancer
JS Macdonald Clinical Oncology Updates 4(3):1-7
2000
Alterations in exon 4 of the p53 gene in gastric carcinoma
T Shepherd;D Tolbert;J Benedetti;J Macdonald;G Stemmerman;J Wiest;G DeVoe;MA Miller;J Wang;A Noffsinger;C Fenoglio-Preiser Gastroenterology 118:1039-1044
Postoperative combined radiation and chemotherapy improves disease-free survival (DFS) and overall survival (OS) in resected adenocarcinoma of the stomach and G.E. junction. results of Intergroup study INT-0116 (SWOG 9008)
JS Macdonald;S Smalley;J Benedetti;N Estes;DG Haller;JA Ajani;LL Gunderson;M Jessup;JA Martenson Proc of the American Society of Clinical Oncology 19:1a(#1)
Intergroup 0116 (SWOG 9008)- Phase III trial of postoperative adjuvant radiochemotherapy for high risk gastric and gastroesophageal (GE) junction adenocarcinoma (ACA): evaluation of efficacy and radiotherapy treatment planning
S Smalley;J Benedetti;L Gunderson;J Martenson;J Tepper;K Kiel;A Lichter;J Forman;J Macdonald Int J Radiat Oncol Biol Phys 48(3)Suppl:111-112
Thioredoxin, a putative oncogene product is overexpressed in gastric carcinoma and associated with increased proliferation and increased cell survival
TM Grogan;C Fenoglio-Prieser;R Zeheb;W Bellamy;Y Frutiger;E Vela;G Stemmerman;J Macdonald;L Richter;A Gallegos;G Powis Human Pathology 31(4):475-481
A simple classification of gastric cancer
OJ Kim;G Stemmermann;A Noffsinger;C Fenoglio-Preiser Modern Pathology 13(1):83a(#474)
1999
p53 immunoreactivity and single-strand conformational polymorphism analysis often fail to predict p53 mutational status.
DM Tolbert;AE Noffsinger;MA Miller;GW DeVoe;GN Stemmermann;JS Macdonald;CM Fenoglio-Preiser Modern Pathology 12(1):54-60
The relation of p53 gene mutations to gastric cancer subsite and phenotype.
D Tolbert;C Fenoglio-Preiser;A Noffsinger;G De Voe;J Macdonald;J Benedetti;GM Stemmermann Cancer Causes and Control 10:227-231
Alterations in exon 4 of the p53 gene in gastric cancer.
D Tolbert;AE Noffsinger;GN Stemmermann;CM Fenoglio-Preiser Proc of the American Association for Cancer Research 40:346(#2289)
Minisatellite instability in gastric cancer
YE Nikiforov;T Schulte;GN Stemmermann;AN Noffsinger;CM Fenoglio-Preiser Laboratory Investigation 79:81A(#463)
1998
Inadequate documentation and resection for gastric cancer in the United States: A preliminary report.
NC Estes;JS Macdonald;K Touijer;J Benedetti;J Jacobson The American Surgeon 64(7):680-685
1997
Detection of microsatellite instability and p53 gene mutations in advanced gastric carcinomas.
D Tolbert;A Noffsinger;G Stemmermann;C Fenoglio-Preiser International Academy of Pathology Book of Abstracts :65A(#369)
1996
Immunohistochemical analysis of bcl-2 family proteins in adenocarcinomas of the stomach.
M Krajewska;CM Fenoglio-Preiser;JS Macdonald;G Stemmerman;JC Reed American Journal of Pathology 149(5):1449-1457
Pathologic and phenotypic features of gastric cancer.
CM Fenoglio-Preiser;AE Noffsinger;J Belli;GN Stemmermann Seminars in Oncology 23(3):292-306