SWOG clinical trial number
SWOG-8417/19

Evaluation of Two Consolidation Regimens in the Treatment of Adult Acute Lymphoblastic Leukemia

Closed
Phase
Accrual
100%
Published
Abbreviated Title
Evaluation of Two Consolidation Regimens in the Treatment of Adult Acute Lymphoblastic Leukemia
Activated
06/14/1985
Closed
11/15/1991

Research committees

Leukemia

Publication Information Expand/Collapse

2001

Comparison of the L10M consolidation regimen to an alternative regimen including escalating methotrexate/L-asparaginase for adult acute lymphoblastic leukemia: a Southwest Oncology Group study

SH Petersdorf;KJ Kopecky;DR Head;DH Boldt;SP Balcerzak;T Wun;V Roy;RW Veith;FR Appelbaum Leukemia 15:208-216

2000

Cell cycle regulatory gene abnormalities are important determinants of leukemogenesis and disease biology in adult a2000 Apr 1;95(7):2364-71.cute lymphoblastic leukemia

W Stock;T Tsai;C Golden;C Rankin;D Sher;ML Slovak;MG Pallavicini;JP Radich;DH Boldt Blood Apr 1;95(7):2364-71

1997

Detection of cancer cells with PCR-telomerase assay in human tumor biopsies.

E Raymond;S Sharma;D Sun;RE Champlin;H Soda;DH Boldt;DD Von Hoff Proc of the American Society of Clinical Oncology 16:93a

Inactivation of cell cycle regulatory genes occurs frequently in adult acute lymphoblastic leukemia (ALL): potential role for p16, p13, Rb, and p53 in leukemogenesis.

W Stock;C Rankin;D Sher;P Eagan;T Tsai;D Boldt Proc of the American Society of Clinical Oncology 16:552a(#1993)

1996

Comparison of tumor suppressor gene inactivation in de novo and relapsed adult acute lymphoblastic leukemia (ALL).

T Tsai;S Davalath;C Rankin;F Appelbaum;DH Boldt American Society of Clinical Oncology 15:358(#1052)

Tumor suppressor gene alteration in adult acute lymphoblastic leukemia (ALL). Analysis of retinoblastoma (Rb) and p53 gene expression in lymphoblasts of patients with de novo, relapsed, or refractory ALL treated in Southwest Oncology Group studies.

T Tsai;S Davalath;C Rankin;JP Radich;D Head;FR Appelbaum;DH Boldt Leukemia 10:1901-1910

1995

Inactivation of tumor suppressor genes, Rb1, and p53, in adult ALL. The Southwest Oncology Group experience.

S Davalath;C Rankin;J Radich;K Kopecky;M Gulley;F Appelbaum;DH Boldt ASCO 14:336(#1008)

1994

Detection of BCR-ABL fusion genes in adult acute lymphoblastic leukemia by the polymerase chain reaction.

JP Radich;KJ Kopecky;DH Boldt;D Head;ML Slovak;R Babu;J Kirk;A Lee;P Kessler;F Appelbaum;G Gehly Leukemia 8(10):1688-1695

1993

A comparison of two consolidated regimens in the treatment of adult acute lymphoblastic leukemia (ALL): The results of the Southwest Oncology Group studies (SWOG) 8417/19

S Petersdorf;KJ Kopecky;D Head;D Boldt;F Appelbaum Blood 82(10)(Suppl):193a(#759)

1992

Expression of myeloid antigens in adult acute lymphoblastic leukemia: The Southwest Oncology Group experience.

DH Boldt;K Kopecky;D Head;G Gehly;J Radich;FR Appelbaum ASCO 11:263(#863)

1991

Detection of BCR-ABL fusion genes in adult acute lymphoblastic leukemia by the polymerase chain reaction.

G Gehly;K Kopecky;D Boldt;D Head;M Slovak;F Appelbaum;J Radich Blood 78:266a

1990

An outpatient (OP) approach to the delivery of intensive consolidation chemotherapy (CT) to adults with acute lymphoblastic leukemia (ALL).

P Palmer;FJ Meyers Oncology Nursing Forum 17(4):553-558