Clinical Trials

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    Closed
    Phase
    100% Accrual
    Accrual
    100%
    Published
    S1202
    SWOG Clinical Trial Number

    A Randomized Placebo-Controlled Phase III Study of Duloxetine for Treatment of Aromatase Inhibitor (AI)-Associated Musculoskeletal Symptoms in Women with Early Stage Breast Cancer
    Status Notes
    This protocol will be permanently closed to accrual effective 10/1/15.
    Research Committee(s)
    Symptom Control and Quality of Life
    Breast Cancer
    Activated
    05-15-2013
    Closed
    10-01-2015
    ClinicalTrials.gov Registry Number
    NCT01598298
    Closed
    Phase
    100% Accrual
    Accrual
    100%
    Published
    S1115
    SWOG Clinical Trial Number

    Randomized Phase II Clinical Trial of AZD6244 Hydrogen Sulfate (NSC-748727) and MK-2206 (NSC-749607) vs. mFOLFOX in Patients with Metastatic Pancreatic Cancer after Prior Chemotherapy
    Research Committee(s)
    Gastrointestinal Cancer
    Activated
    08-15-2012
    Closed
    05-15-2014
    ClinicalTrials.gov Registry Number
    NCT01658943
    Closed
    Phase
    100% Accrual
    Accrual
    100%
    Published
    S1117
    SWOG Clinical Trial Number

    A Randomized Phase II Study of Azacitidine in Combination with Lenalidomide (NSC-703813) vs. Azacitidine Alone vs. Azacitidine in Combination with Vorinostat (NSC-701852) for Higher-Risk Myelodysplastic Syndromes (MDS) and Chronic Myelomonocytic Leukemia (CMML)
    Research Committee(s)
    Leukemia
    Activated
    03-01-2012
    Closed
    11-14-2014
    ClinicalTrials.gov Registry Number
    NCT01522976
    Closed
    Phase
    100% Accrual
    Accrual
    100%
    Published
    S0927
    SWOG Clinical Trial Number

    Randomized Placebo-Controlled Trial of Omega-3-Fatty Acid for the Control of Aromatase Inhibitor-Induced Musculoskeletal Pain in Women with Early Stage Breast Cancer, Phase III
    Research Committee(s)
    Symptom Control and Quality of Life
    Breast Cancer
    Activated
    02-01-2012
    Closed
    02-01-2013
    ClinicalTrials.gov Registry Number
    NCT01385137
    Closed
    Phase
    100% Accrual
    Accrual
    100%
    Published
    S1119
    SWOG Clinical Trial Number

    Gastric Cancer and Helicobacter Pylori Infection in Lima, Peru: The Role of Water Contamination
    Research Committee(s)
    Prevention & Epidemiology
    Activated
    12-02-2011
    Closed
    08-05-2013
    ClinicalTrials.gov Registry Number
    NCT01512875
    Closed
    Phase
    100% Accrual
    Accrual
    100%
    Published
    S1108
    SWOG Clinical Trial Number

    Phase II Trial of the Aurora Kinase A Inhibitor, MLN8237, in Peripheral T-Cell Non-Hodgkin Lymphoma
    Research Committee(s)
    Lymphoma
    Activated
    10-28-2011
    Closed
    06-06-2013
    Closed
    Phase
    29% Accrual
    Accrual
    29%
    Published
    S1106
    SWOG Clinical Trial Number

    A Randomized Phase II Trial of R-HCVAD-MTX/ARA-C Induction Followed by Consolidation With an Autologous Stem Cell Transplant vs. R-Bendamustine Induction Followed by Consolidation With an Autologous Stem Cell Transplant for Patients </= 65 Years of Age With Previously Untreated Mantle Cell Lymphoma
    Research Committee(s)
    Lymphoma
    Activated
    10-01-2011
    Closed
    06-26-2013
    ClinicalTrials.gov Registry Number
    NCT01412879
    Closed
    Phase
    98% Accrual
    Accrual
    98%
    Published
    S1014
    SWOG Clinical Trial Number

    Abiraterone Acetate Treatment for Prostate Cancer Patients with a PSA of More Than Four Following Initial Androgen Deprivation Therapy, Phase II.
    Research Committee(s)
    Genitourinary Cancer
    Activated
    08-09-2011
    Closed
    08-01-2013
    ClinicalTrials.gov Registry Number
    NCT01309672
    Closed
    Phase
    100% Accrual
    Accrual
    100%
    Published
    S1005
    SWOG Clinical Trial Number

    A Phase II Study of MK-2206 (NSC-749607) as Second Line Therapy for Advanced Gastric and Gastroesophageal Junction Cancer
    Research Committee(s)
    Gastrointestinal Cancer
    Activated
    01-01-2011
    Closed
    05-01-2013
    Closed
    Phase
    100% Accrual
    Accrual
    100%
    Published
    S0925
    SWOG Clinical Trial Number

    A Randomized Phase II Study of Androgen Deprivation Combined with IMC-A12 Versus Androgen Deprivation Alone for Patients with New Hormone-Sensitive Metastatic Prostate Cancer
    Research Committee(s)
    Genitourinary Cancer
    Activated
    12-15-2010
    Closed
    12-01-2012
    ClinicalTrials.gov Registry Number
    NCT01120236
    Closed
    Phase
    100% Accrual
    Accrual
    100%
    Published
    S0806
    SWOG Clinical Trial Number

    A Phase I/II Trial of Vorinostat (SAHA) (NSC-701852) in Combination with Rituximab-CHOP in Patients with Newly Diagnosed Advanced Stage Diffuse Large B-Cell Lymphoma (DLBCL)
    Research Committee(s)
    Lymphoma
    Activated
    11-15-2010
    Closed
    10-01-2013
    ClinicalTrials.gov Registry Number
    NCT00972478
    Closed
    Phase
    45% Accrual
    Accrual
    45%
    Published
    S0933
    SWOG Clinical Trial Number

    Phase II Study of RO4929097 (NSC-749225) in Advanced Melanoma
    Research Committee(s)
    Melanoma
    Activated
    10-28-2010
    Closed
    11-15-2011
    ClinicalTrials.gov Registry Number
    NCT01120275
    Closed
    Phase
    100% Accrual
    Accrual
    100%
    Published
    S0910
    SWOG Clinical Trial Number

    A Phase II Study of Epratuzumab in Combination with Cytarabine and Clofarabine for Patients with Relapsed or Refractory Precursor B-cell Acute Lymphoblastic Leukemia
    Research Committee(s)
    Leukemia
    Activated
    08-15-2010
    Closed
    07-01-2012
    Closed
    Phase
    73% Accrual
    Accrual
    73%
    Published
    S0941
    SWOG Clinical Trial Number

    Phase II Study of Sorafenib (NSC-724772) and Erlotinib (NSC-718781) in Patients with Advanced Gallbladder Carcinoma or Cholangiocarcinoma
    Research Committee(s)
    Gastrointestinal Cancer
    Activated
    04-15-2010
    Closed
    09-15-2011
    ClinicalTrials.gov Registry Number
    NCT01093222
    Closed
    Phase
    100% Accrual
    Accrual
    100%
    Published
    S0800
    SWOG Clinical Trial Number

    A Randomized Phase II Trial of Weekly Nanoparticle Albumin Bound Paclitaxel (Nab-Paclitaxel) (NSC-736631) With or Without Bevacizumab, Either Preceded by or Followed by Q 2 Week Doxorubicin (A) and Cyclophosphamide (C) Plus Pegfilgrastim (Peg-G) as Neoadjuvant Therapy for Inflammatory and Locally Advanced Her-2/Neu Negative Breast Cancer
    Research Committee(s)
    Breast Cancer
    Activated
    04-01-2010
    Closed
    10-01-2012
    Closed
    Phase
    91% Accrual
    Accrual
    91%
    Published
    S0905
    SWOG Clinical Trial Number

    A Phase I / Randomized Phase II Study of Cediranib (NSC #732208) Versus Placebo in Combination with Cisplatin and Pemetrexed in Chemonaive Patients with Malignant Pleural Mesothelioma
    Status Notes
    This study permanently closed to accrual February 15, 2016.
    Research Committee(s)
    Lung Cancer
    Activated
    03-15-2010
    Closed
    02-15-2016
    ClinicalTrials.gov Registry Number
    NCT01064648
    Closed
    Phase
    99% Accrual
    Accrual
    99%
    Published
    S0904
    SWOG Clinical Trial Number

    Randomized Phase II Study of Docetaxel Followed by Vandetanib (ZD6474) vs. Docetaxel plus Vandetanib in Patients with Persistent or Recurrent Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Carcinoma
    Research Committee(s)
    Gynecologic Cancer
    Activated
    03-15-2010
    Closed
    08-01-2011
    Closed
    Phase
    100% Accrual
    Accrual
    100%
    Published
    S0715
    SWOG Clinical Trial Number

    Randomized Placebo-Controlled Trial of Acetyl L-Carnitine for the Prevention of Taxane Induced Neuropathy
    Research Committee(s)
    Symptom Control and Quality of Life
    Breast Cancer
    Cancer Survivorship
    Molecular Epidemiology
    Activated
    09-15-2009
    Closed
    02-01-2011
    Closed
    Phase
    100% Accrual
    Accrual
    100%
    Published
    S0805
    SWOG Clinical Trial Number

    Phase II Study of Combination of Hyper-CVAD and Dasatinib with or without Allogeneic Stem Cell transplant in Patients with Philadelphia (Ph) Chromosome Positive and/or Bcr-Abl Positive Acute Lymphoblastic Leukemia (ALL)
    Research Committee(s)
    Leukemia
    Activated
    09-01-2009
    ClinicalTrials.gov Registry Number
    NCT00390793
    Closed
    Phase
    78% Accrual
    Accrual
    78%
    Published
    S0819
    SWOG Clinical Trial Number

    A Randomized, Phase III Study Comparing Carboplatin/Paclitaxel or Carboplatin/Paclitaxel/Bevacizumab with or without Concurrent Cetuximab in Patients with Advanced Non-Small Cell Lung Cancer (NSCLC)
    Status Notes
    Status Notes: NOTE: The url for ordering specimen kits for this study has changed. Please use the following link: https://ricapps.nationwidechildrens.org/KitManagement
    Research Committee(s)
    Lung Cancer
    Activated
    07-15-2009
    Closed
    05-01-2015
    ClinicalTrials.gov Registry Number
    NCT00946712