A Randomized Phase III Trial of IV Carboplatin (AUC 6) and Paclitaxel 175 mg/m2 Q 21 Days X 3 Courses Plus Low Dose Paclitaxel 40 mg/m2/wk Versus IV Carboplatin (AUC 6) and Paclitaxel 175 mg/m2 Q 21 Days X 3 Courses Plus Observation in Patients With Early Stage Ovarian Carcinoma.

Closed

Phase

Published

Abbreviated Title

OVARIAN

Activated

11/15/2000

Closed

08/15/2003

Participants

NCORP, Members

Research committees

Gynecologic Cancer

Treatment

Paclitaxel Carboplatin

Eligibility Criteria Expand/Collapse

Histopathologic diagnosis of epithelial ovarian cancer. After definitive staging procedure, pts are completely resected. Pts must be entered within 6 wks of staging surgery. No previous treatment for this malignancy except surgical therapy. Bilirubin =< 1.5 times normal; alkaline phosphatase and SGOT =< 3 times normal. Performance status 0-3.