Phase III Randomized Study of Concurrent Tretinoin and Chemotherapy With or Without Arsenic Trioxide (AS2O3) (NSC #706363) as Initial Consolidation Therapy Followed by Intermittent Tretinoin Maintenance Therapy Versus Observation for Patients with Untreated Acute Promyelocytic Leukemia
Research committees
Treatment
Eligibility Criteria Expand/Collapse
Publication Information Expand/Collapse
2017
PMid: PMID28082441 | PMC number: PMC5374291
2014
Telomere length recovery strongly predicts overall survival in acute promyelocytic leukemia (http://www.bloodjournal.org/content/124/21/2375)
PMid: PMID24160850 | PMC number: PMC4273565
2012
PMid: PMID22734072 | PMC number: PMC3437597
2010
Arsenic trioxide improves event-free and over-all survival for adults with acute promyelocytic leukemia: North American Leukemia Intergroup Study C9710 [PMID20705755; PMC2981533]
Clonal markers in relapsed acute promyelocytic leukemia (APL): clinicopathological associations and relation to all-trans retinoic acid (ATRA) treatment on intergroup phase III trial C9710
2008
Arsenic trioxide consolidation improves event-free and overall survival among patients with newly diagnosed acute promyelocytic leukemia: North American Intergroup protocol C9710
2007
Effect of consolidation with arsenic trioxide (As2O3) on event-free survival (EFS) and overall survival (OS) among patients with newly diagnosed acute promyelocytic leukemia (APL): North American Intergroup Protocol C9710
Prognostic significance of initial clinical and molecular genetic features of acute promyelocytic leukemia (APL): Results from the North American Intergroup Trial, C9710
2006
Relapse of acute promyelocytic leukemia with PML-RARa mutant subclones independent of proximate all-trans retinoic acid selection pressure
Frequent PML-RARa mutations in relapse patients on acute promyelocytic leukemia (APL) intergroup Phase III trial C9710