PCPT Biorepository

The Prostate Cancer Prevention Trial (PCPT) was a SWOG Cancer Research Network-coordinated study designed to test whether the drug finasteride (Proscar®) would prevent prostate cancer in men ages 55 and older. This study was closed on June 24, 2003 because the study objective had been reached. The results of the study, which did find a preventive benefit for the drug, were published as "The Influence of Finasteride on the Development of Prostate Cancer," in the New England Journal of Medicine on July 17, 2003.

PCPT Resources

1. Learn more about PCPT
   1. NCI PCPT site
   2. Prostate cancer prevention in PDQ
2. Summary of trial and results
   1. PCPT - Summary of primary results
   2. Data elements collected - summary table
   3. P01 - Biology of the Prostate Cancer Prevention Trial (PCPT)
3. Specimens
   1. Blood and tissue acquisition protocols
   2. Biologic samples available
   3. Existing biologic measures
   4. Approved requests
4. Study documents
   1. Protocol (S9217)
   2. Informed consent
   3. Major publications regarding primary trial results, study implementation references; instructions on how to get to full Publication list on swog.org
   4. Study forms
5. PCPT data
   1. Baseline characteristics
   2. Endpoints (number of prostate cancers, other cancers, deaths)

Biorepository resources from the Selenium and Vitamin E Cancer Trial (SELECT), which also studied prostate cancer prevention, are also available.